Unlocking Key Models for Schizophrenia Research: Comprehensive Analysis of Mechanisms, Workflow, and Validation Data of PCP-Induced Animal Models

This poster will provide you with the following details：

Authoritative Model Analysis

Delves into the neural mechanisms of Phencyclidine (PCP)-induced models, highlighting their unique advantages in simulating positive/negative symptoms and cognitive deficits of schizophrenia. Serves as a reliable platform for disease mechanism research and drug development.

Visualized Step-by-Step Protocol

Clearly demonstrates standardized workflows—from animal modeling and behavioral testing to data analysis—enabling rapid replication of high-consistency models and saving valuable R&D time.

Critical Behavioral Validation Data

Focuses on three core experimental outcomes, providing directly applicable empirical support for protocol design:

• Open field test: Quantifies spontaneous activity and anxiety-like behavior, revealing hypoactivity linked to negative symptoms.
• Prepulse inhibition (PPI) test: Precisely detects sensorimotor gating deficits, modeling core features of positive symptoms.
• Novel object recognition (NOR) test: Objectively assesses working memory and cognitive flexibility impairments.

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